Gene

pgap1

ID
ZDB-GENE-090313-216
Name
post-GPI attachment to proteins inositol deacylase 1
Symbol
pgap1 Nomenclature History
Previous Names
  • si:dkey-191g15.7
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Predicted to have phosphatidylinositol deacylase activity. Predicted to be involved in GPI anchor metabolic process and endoplasmic reticulum to Golgi vesicle-mediated transport. Predicted to localize to endoplasmic reticulum. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability. Orthologous to human PGAP1 (post-GPI attachment to proteins inositol deacylase 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Chassaing et al., 2012
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pgap1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Neurodevelopmental disorder with dysmorphic features, spasticity, and brain abnormalities 615802
Associated With pgap1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR012908 GPI inositol-deacylase PGAP1-like
Family IPR039529 GPI inositol-deacylase
Homologous_superfamily IPR029058 Alpha/Beta hydrolase fold
Domain Details Per Protein
Protein Length Alpha/Beta hydrolase fold GPI inositol-deacylase GPI inositol-deacylase PGAP1-like
UniProtKB:A0A8M9PSV5 939
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA pgap1-201 (1) Ensembl 3,598 nt
mRNA pgap1-202 (1) Ensembl 2,923 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations