Gene
slc4a11
- ID
- ZDB-GENE-090313-183
- Name
- solute carrier family 4 member 11
- Symbol
- slc4a11 Nomenclature History
- Previous Names
-
- si:dkey-12j14.4
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to have transmembrane transporter activity. Predicted to be involved in ion homeostasis and transmembrane transport. Predicted to localize to basolateral plasma membrane. Is expressed in several structures, including eye; gill; heart; muscle; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in Fuchs' endothelial dystrophy; congenital hereditary endothelial dystrophy of cornea; and corneal dystrophy-perceptive deafness syndrome. Orthologous to human SLC4A11 (solute carrier family 4 member 11).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 1 figure from Lee et al., 2011
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
congenital hereditary endothelial dystrophy of cornea | Alliance | Corneal endothelial dystrophy, autosomal recessive | 217700 |
corneal dystrophy-perceptive deafness syndrome | Alliance | Corneal endothelial dystrophy and perceptive deafness | 217400 |
Fuchs' endothelial dystrophy | Alliance | Corneal dystrophy, Fuchs endothelial, 4 | 613268 |
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | Bicarbonate transporter, eukaryotic | Bicarbonate transporter-like, transmembrane domain | Phosphotransferase/anion transporter |
---|---|---|---|---|
UniProtKB:A0A8M1NRH1
|
846 | |||
UniProtKB:A0A8M2B2N8
|
877 |
Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
slc4a11-201
(1)
|
Ensembl | 2,798 nt | ||
mRNA |
slc4a11-202
(1)
|
Ensembl | 2,349 nt | ||
mRNA |
slc4a11-203
(1)
|
Ensembl | 2,457 nt |
Interactions and Pathways
No data available
Plasmids
No data available