Gene
kcnq5b
- ID
- ZDB-GENE-090312-178
- Name
- potassium voltage-gated channel, KQT-like subfamily, member 5b
- Symbol
- kcnq5b Nomenclature History
- Previous Names
-
- kcnq5
- si:dkey-7m11.2
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to have calmodulin binding activity and delayed rectifier potassium channel activity. Predicted to be involved in potassium ion transmembrane transport. Predicted to localize to voltage-gated potassium channel complex. Human ortholog(s) of this gene implicated in autosomal dominant mental retardation 46. Is expressed in brain; heart; and inner ear. Orthologous to human KCNQ5 (potassium voltage-gated channel subfamily Q member 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal dominant intellectual developmental disorder 46 | Alliance | Intellectual developmental disorder, autosomal dominant 46 | 617601 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Ion transport domain | Potassium channel, voltage dependent, KCNQ | Potassium channel, voltage dependent, KCNQ, C-terminal | Voltage-dependent channel domain superfamily |
|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PEL0
|
469 | ||||
|
UniProtKB:A0A8M9PPV9
|
835 | ||||
|
UniProtKB:F1RB62
|
974 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
kcnq5b-201
(1)
|
Ensembl | 4,059 nt | ||
| mRNA |
kcnq5b-202
(1)
|
Ensembl | 1,233 nt | ||
| mRNA |
kcnq5b-203
(1)
|
Ensembl | 579 nt |
Interactions and Pathways
No data available
Plasmids
No data available