Gene
mcf2la
- ID
- ZDB-GENE-090312-122
- Name
- mcf.2 cell line derived transforming sequence-like a
- Symbol
- mcf2la Nomenclature History
- Previous Names
-
- mcf2l
- si:dkey-269p14.1
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to have guanyl-nucleotide exchange factor activity. Predicted to be involved in intracellular signal transduction. Is expressed in several structures, including Kupffer's vesicle; chondrocyte; immature eye; mandibular arch skeleton; and yolk syncytial layer. Orthologous to human MCF2L (MCF.2 cell line derived transforming sequence like).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 1 figure from Mitchell et al., 2013
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR001331 | Guanine-nucleotide dissociation stimulator, CDC24, conserved site |
Domain | IPR000219 | Dbl homology (DH) domain |
Domain | IPR001251 | CRAL-TRIO lipid binding domain |
Domain | IPR001452 | SH3 domain |
Domain | IPR001849 | Pleckstrin homology domain |
Domain | IPR035532 | DBS, SH3 domain |
Domain | IPR035534 | DBS, PH domain |
Family | IPR051336 | Rho GTPase-activating Guanine Nucleotide Exchange Factors |
Homologous_superfamily | IPR011993 | PH-like domain superfamily |
Homologous_superfamily | IPR035899 | Dbl homology (DH) domain superfamily |
Homologous_superfamily | IPR036028 | SH3-like domain superfamily |
Homologous_superfamily | IPR036865 | CRAL-TRIO lipid binding domain superfamily |
Domain Details Per Protein
Protein | Length | CRAL-TRIO lipid binding domain | CRAL-TRIO lipid binding domain superfamily | Dbl homology (DH) domain | Dbl homology (DH) domain superfamily | DBS, PH domain | DBS, SH3 domain | Guanine-nucleotide dissociation stimulator, CDC24, conserved site | PH-like domain superfamily | Pleckstrin homology domain | Rho GTPase-activating Guanine Nucleotide Exchange Factors | SH3 domain | SH3-like domain superfamily |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
UniProtKB:A0A8M9Q0I6
|
1182 | ||||||||||||
UniProtKB:A0A8M2BIA4
|
1167 | ||||||||||||
UniProtKB:A0A8M9QAY2
|
1221 | ||||||||||||
UniProtKB:A0A8M9QG01
|
1206 | ||||||||||||
UniProtKB:A0A8M9QG32
|
1034 | ||||||||||||
UniProtKB:A0A8M9QAZ1
|
1191 | ||||||||||||
UniProtKB:A0A8M2BID6
|
1196 | ||||||||||||
UniProtKB:A0A8M9QB00
|
1191 | ||||||||||||
UniProtKB:A0A8M1QR18
|
1142 |
Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
mcf2la-201
(1)
|
Ensembl | 4,010 nt | ||
mRNA |
mcf2la-203
(1)
|
Ensembl | 637 nt | ||
mRNA |
mcf2la-204
(1)
|
Ensembl | 3,541 nt | ||
ncRNA |
mcf2la-003
(1)
|
Ensembl | 195 nt |
Interactions and Pathways
No data available
Plasmids
No data available