Gene

ogdhb

ID

ZDB-GENE-090311-8

Name

oxoglutarate dehydrogenase b

Symbol

ogdhb Nomenclature History

Previous Names

si:ch211-229p19.3

Type

protein_coding_gene

Location

Chr: 10 Mapping Details/Browsers

Description

Predicted to have oxoglutarate dehydrogenase (succinyl-transferring) activity. Involved in heart contraction. Predicted to localize to mitochondrion and oxoglutarate dehydrogenase complex. Orthologous to human OGDH (oxoglutarate dehydrogenase).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ogdhb Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
oxoglutarate dehydrogenase deficiency	Alliance	Oxoglutarate dehydrogenase deficiency	203740

Associated With ogdhb Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001017	Dehydrogenase, E1 component
Domain	IPR005475	Transketolase-like, pyrimidine-binding domain
Domain	IPR031717	2-oxoglutarate dehydrogenase E1 component/KDG, C-terminal
Domain	IPR032106	2-oxoglutarate dehydrogenase E1 component, N-terminal domain
Family	IPR011603	2-oxoglutarate dehydrogenase E1 component
Homologous_superfamily	IPR029061	Thiamin diphosphate-binding fold
Homologous_superfamily	IPR042179	Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain superfamily

Domain Details Per Protein

Protein	Length	2-oxoglutarate dehydrogenase E1 component	2-oxoglutarate dehydrogenase E1 component/KDG, C-terminal	2-oxoglutarate dehydrogenase E1 component, N-terminal domain	Dehydrogenase, E1 component	Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain superfamily	Thiamin diphosphate-binding fold	Transketolase-like, pyrimidine-binding domain
UniProtKB:E7EZ05 InterPro	1023
UniProtKB:A0A8M9PUH2 InterPro	1020

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	ogdhb-202 (1) Ensembl	Ensembl	6,065 nt	Select Tool
mRNA	ogdhb-203 (1) Ensembl	Ensembl	3,404 nt	Select Tool ZFIN BLAST
ncRNA	ogdhb-002 (1) Ensembl	Ensembl	414 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations