Gene
ap2a1
- ID
- ZDB-GENE-090302-2
- Name
- adaptor related protein complex 2 subunit alpha 1
- Symbol
- ap2a1 Nomenclature History
- Previous Names
-
- fa95c07
- si:ch211-195b15.3
- wu:fa95c07 (1)
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to have clathrin adaptor activity. Involved in dorsal/ventral axis specification and hematopoietic stem cell differentiation. Predicted to localize to AP-2 adaptor complex. Orthologous to human AP2A1 (adaptor related protein complex 2 subunit alpha 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR002553 | Clathrin/coatomer adaptor, adaptin-like, N-terminal |
| Domain | IPR003164 | Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain |
| Domain | IPR008152 | Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain |
| Family | IPR017104 | Adaptor protein complex AP-2, alpha subunit |
| Family | IPR050840 | Adaptor Complexes Large Subunit |
| Homologous_superfamily | IPR009028 | Coatomer/calthrin adaptor appendage, C-terminal subdomain |
| Homologous_superfamily | IPR011989 | Armadillo-like helical |
| Homologous_superfamily | IPR012295 | TBP domain superfamily |
| Homologous_superfamily | IPR013041 | Clathrin adaptor, appendage, Ig-like subdomain superfamily |
| Homologous_superfamily | IPR016024 | Armadillo-type fold |
Domain Details Per Protein
| Protein | Length | Adaptor Complexes Large Subunit | Adaptor protein complex AP-2, alpha subunit | Armadillo-like helical | Armadillo-type fold | Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain | Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain | Clathrin adaptor, appendage, Ig-like subdomain superfamily | Clathrin/coatomer adaptor, adaptin-like, N-terminal | Coatomer/calthrin adaptor appendage, C-terminal subdomain | TBP domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3AQZ7
|
959 | ||||||||||
|
UniProtKB:A0A8M2BBC5
|
980 | ||||||||||
|
UniProtKB:A0A8M3B8D0
|
984 | ||||||||||
|
UniProtKB:A0A8M2BBK5
|
939 | ||||||||||
|
UniProtKB:A0A8M2BB77
|
963 |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance