Gene
nectin1a
- ID
- ZDB-GENE-090224-1
- Name
- nectin cell adhesion molecule 1a
- Symbol
- nectin1a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Acts upstream of or within primary palate development. Predicted to be located in membrane. Predicted to be active in adherens junction. Is expressed in several structures, including hindbrain; mandibular arch skeleton; optic vesicle; solid lens vesicle; and visual system. Human ortholog(s) of this gene implicated in cleft lip; cleft lip-palate-ectodermal dysplasia syndrome; cleft palate; and ectodermal dysplasia. Orthologous to human NECTIN1 (nectin cell adhesion molecule 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Liu et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| cleft lip-palate-ectodermal dysplasia syndrome | Alliance | Cleft lip/palate-ectodermal dysplasia syndrome | 225060 |
| cleft lip-palate-ectodermal dysplasia syndrome | Alliance | Orofacial cleft 7 | 225060 |
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
| Protein | Length |
|---|---|
|
UniProtKB:A0A8M2B818
|
479 |
|
UniProtKB:A0A8M2B8A6
|
496 |
|
UniProtKB:B0JYH7
|
475 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
nectin1a-201
(1)
|
Ensembl | 783 nt | ||
| mRNA |
nectin1a-202
(1)
|
Ensembl | 1,796 nt |
Interactions and Pathways
No data available
Plasmids
No data available