Gene

myhb

ID
ZDB-GENE-081124-1
Name
myosin, heavy chain b
Symbol
myhb Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to enable actin filament binding activity and microfilament motor activity. Predicted to be involved in muscle contraction. Predicted to be part of myosin II complex. Predicted to be active in cytoplasm and myosin filament. Human ortholog(s) of this gene implicated in multiple pterygium syndrome and muscle tissue disease (multiple). Orthologous to several human genes including MYH4 (myosin heavy chain 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Mazzolini et al., 2022
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With myhb Human Ortholog
No data available
Associated With myhb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002928 Myosin tail
Domain IPR004009 Myosin, N-terminal, SH3-like
Homologous_superfamily IPR008989 Myosin S1 fragment, N-terminal
Homologous_superfamily IPR014751 DNA repair protein XRCC4-like, C-terminal
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR036961 Kinesin motor domain superfamily
Domain Details Per Protein
Protein Length DNA repair protein XRCC4-like, C-terminal Kinesin motor domain superfamily Myosin, N-terminal, SH3-like Myosin S1 fragment, N-terminal Myosin tail P-loop containing nucleoside triphosphate hydrolase
UniProtKB:F1QVX3 1937
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA myhb-201 (1) Ensembl 6,204 nt
mRNA myhb-202 (1) Ensembl 5,998 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations