Gene
fmnl2a
- ID
- ZDB-GENE-081105-70
- Name
- formin-like 2a
- Symbol
- fmnl2a Nomenclature History
- Previous Names
-
- fmnl2
- si:ch211-279a7.1
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Description
- Predicted to have actin filament binding activity. Predicted to be involved in cell migration; cortical actin cytoskeleton organization; and regulation of cell shape. Predicted to localize to cytosol. Is expressed in several structures, including blood vessel; nervous system; neuroectoderm; optic cup; and polster. Orthologous to human FMNL2 (formin like 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR010472 | Formin, FH3 domain |
| Domain | IPR010473 | Formin, GTPase-binding domain |
| Domain | IPR014767 | Diaphanous autoregulatory (DAD) domain |
| Domain | IPR014768 | Rho GTPase-binding/formin homology 3 (GBD/FH3) domain |
| Domain | IPR015425 | Formin, FH2 domain |
| Family | IPR043592 | Formin-like protein, animal |
| Homologous_superfamily | IPR011989 | Armadillo-like helical |
| Homologous_superfamily | IPR016024 | Armadillo-type fold |
| Homologous_superfamily | IPR042201 | Formin, FH2 domain superfamily |
Domain Details Per Protein
| Protein | Length | Armadillo-like helical | Armadillo-type fold | Diaphanous autoregulatory (DAD) domain | Formin, FH2 domain | Formin, FH2 domain superfamily | Formin, FH3 domain | Formin, GTPase-binding domain | Formin-like protein, animal | Rho GTPase-binding/formin homology 3 (GBD/FH3) domain |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M6Z832
|
1130 | |||||||||
|
UniProtKB:A0A8M3B5D9
|
1095 | |||||||||
|
UniProtKB:A0A8M6Z0B9
|
1137 | |||||||||
|
UniProtKB:F1QKR1
|
1077 | |||||||||
|
UniProtKB:F1QDA5
|
1088 | |||||||||
|
UniProtKB:A0A8M6Z2M2
|
912 | |||||||||
|
UniProtKB:A0A8M6Z0Z8
|
1084 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
fmnl2a-201
(1)
|
Ensembl | 3,267 nt | ||
| mRNA |
fmnl2a-202
(1)
|
Ensembl | 4,842 nt | ||
| mRNA |
fmnl2a-203
(1)
|
Ensembl | 3,659 nt |
Interactions and Pathways
No data available
Plasmids
No data available