Gene
ano6
- ID
- ZDB-GENE-081104-64
- Name
- anoctamin 6
- Symbol
- ano6 Nomenclature History
- Previous Names
-
- si:ch73-177h5.1
- TMEM16F (1)
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to enable chloride channel activity. Acts upstream of or within sprouting angiogenesis. Predicted to be located in membrane. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in Scott syndrome; ankylosing spondylitis; and inflammatory bowel disease. Orthologous to human ANO6 (anoctamin 6).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Wang et al., 2021
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Delcourt et al., 2015
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Scott syndrome | Alliance | Scott syndrome | 262890 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Anoctamin | Anoctamin, dimerisation domain | Anoctamin, transmembrane domain |
|---|---|---|---|---|
|
UniProtKB:F1QNZ8
|
910 | |||
|
UniProtKB:A0A8M3AR51
|
810 |
Interactions and Pathways
No data available
Plasmids
No data available