Gene
fdft1
- ID
- ZDB-GENE-081104-242
- Name
- farnesyl-diphosphate farnesyltransferase 1
- Symbol
- fdft1 Nomenclature History
- Previous Names
-
- si:ch73-107c13.2
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to have farnesyl-diphosphate farnesyltransferase activity and squalene synthase activity. Predicted to be involved in cholesterol biosynthetic process and farnesyl diphosphate metabolic process. Predicted to localize to endoplasmic reticulum membrane. Orthologous to human FDFT1 (farnesyl-diphosphate farnesyltransferase 1).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
Squalene synthase deficiency | 618156 |
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Conserved_site | IPR019845 | Squalene/phytoene synthase, conserved site |
Domain | IPR033904 | Trans-isoprenyl diphosphate synthases, head-to-head |
Family | IPR002060 | Squalene/phytoene synthase |
Family | IPR006449 | Squalene synthase-like |
Family | IPR044844 | Trans-isoprenyl diphosphate synthases, eukaryotic-type |
Homologous_superfamily | IPR008949 | Isoprenoid synthase domain superfamily |
Domain Details Per Protein
Protein | Length | Isoprenoid synthase domain superfamily | Squalene/phytoene synthase | Squalene/phytoene synthase, conserved site | Squalene synthase-like | Trans-isoprenyl diphosphate synthases, eukaryotic-type | Trans-isoprenyl diphosphate synthases, head-to-head |
---|---|---|---|---|---|---|---|
UniProtKB:A0A0R4IVV5
|
418 | ||||||
UniProtKB:A0A8M9PPK1
|
447 |
Interactions and Pathways
No data available
Plasmids
No data available