Gene

rnf216

ID
ZDB-GENE-081104-199
Name
ring finger protein 216
Symbol
rnf216 Nomenclature History
Previous Names
  • si:ch211-255l18.3
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Involved in camera-type eye development and cerebellum development. Human ortholog(s) of this gene implicated in Gordon Holmes syndrome. Orthologous to human RNF216 (ring finger protein 216).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Margolin et al., 2013
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With rnf216 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Gordon Holmes syndrome Alliance Cerebellar ataxia and hypogonadotropic hypogonadism 212840
Associated With rnf216 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR044066 TRIAD supradomain
Domain IPR047544 E3 ubiquitin-protein ligase RNF216, RING finger, HC subclass
Domain IPR047545 E3 ubiquitin-protein ligase RNF216, BRcat domain
Domain IPR047546 E3 ubiquitin-protein ligase RNF216, Rcat domain
Family IPR051628 Linear Ubiquitination-Associated E3 Ligases
Homologous_superfamily IPR013083 Zinc finger, RING/FYVE/PHD-type
Domain Details Per Protein
Protein Length E3 ubiquitin-protein ligase RNF216, BRcat domain E3 ubiquitin-protein ligase RNF216, Rcat domain E3 ubiquitin-protein ligase RNF216, RING finger, HC subclass Linear Ubiquitination-Associated E3 Ligases TRIAD supradomain Zinc finger, RING/FYVE/PHD-type
UniProtKB:E7F859 834
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA rnf216-201 (1) Ensembl 2,927 nt
mRNA rnf216-202 (1) Ensembl 7,522 nt
mRNA rnf216-203 (1) Ensembl 2,490 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations