Gene
htr2b
- ID
- ZDB-GENE-081022-57
- Name
- 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
- Symbol
- htr2b Nomenclature History
- Previous Names
-
- zgc:194094
- zgc:194119
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to enable G protein-coupled serotonin receptor activity and neurotransmitter receptor activity. Acts upstream of or within heart development. Predicted to be located in membrane and synapse. Predicted to be active in dendrite and plasma membrane. Is expressed in brain; heart; male organism; and ventral mandibular arch. Human ortholog(s) of this gene implicated in metabolic dysfunction-associated steatohepatitis and steatotic liver disease. Orthologous to human HTR2B (5-hydroxytryptamine receptor 2B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Kent et al., 2022
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | 5-Hydroxytryptamine 2B receptor | 5-hydroxytryptamine receptor family | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like |
|---|---|---|---|---|---|
|
UniProtKB:Q0GH74
|
443 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available