Gene
adrb3b
- ID
- ZDB-GENE-081022-154
- Name
- adrenoceptor beta 3b
- Symbol
- adrb3b Nomenclature History
- Previous Names
-
- zgc:194843
- zgc:194852
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to enable beta3-adrenergic receptor activity and epinephrine binding activity. Predicted to be involved in adenylate cyclase-activating adrenergic receptor signaling pathway; norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure; and positive regulation of MAPK cascade. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in brain. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); arthritis (multiple); dilated cardiomyopathy 1H; metabolic dysfunction-associated steatotic liver disease; and type 2 diabetes mellitus. Orthologous to human ADRB3 (adrenoceptor beta 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Wang et al., 2009
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Wang et al., 2009
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like |
|---|---|---|---|
|
UniProtKB:B3DIE4
|
405 | ||
|
UniProtKB:A0A8M9QKR9
|
417 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
adrb3b-201
(1)
|
Ensembl | 1,676 nt |
Interactions and Pathways
No data available
Plasmids
No data available