Gene
adrb3a
- ID
- ZDB-GENE-080917-21
- Name
- adrenoceptor beta 3a
- Symbol
- adrb3a Nomenclature History
- Previous Names
-
- im:7154935 (1)
- si:ch211-215f19.1
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to enable beta3-adrenergic receptor activity and epinephrine binding activity. Predicted to be involved in adenylate cyclase-activating adrenergic receptor signaling pathway and norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in blood; brain; hatching gland; intermediate cell mass of mesoderm; and polster. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); arthritis (multiple); dilated cardiomyopathy 1H; obesity; and type 2 diabetes mellitus. Orthologous to human ADRB3 (adrenoceptor beta 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7154935 (9 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like |
|---|---|---|---|
|
UniProtKB:B0UYT9
|
413 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
adrb3a-201
(1)
|
Ensembl | 2,024 nt | ||
| mRNA |
adrb3a-202
(1)
|
Ensembl | 1,317 nt |
Interactions and Pathways
No data available
Plasmids
No data available