Gene
map2k4b
- ID
- ZDB-GENE-080721-13
- Name
- mitogen-activated protein kinase kinase 4b
- Symbol
- map2k4b Nomenclature History
- Previous Names
-
- mkk4b (1)
- zgc:194486
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to have JUN kinase kinase activity and protein serine/threonine kinase activity. Involved in convergent extension involved in gastrulation. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in ovarian serous carcinoma; pancreatic cancer; and urinary bladder cancer. Orthologous to human MAP2K4 (mitogen-activated protein kinase kinase 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Seo et al., 2010
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Seo et al., 2010
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|
|
UniProtKB:A0A8M9QMM1
|
501 | ||||
|
UniProtKB:A0A8M2BK72
|
482 | ||||
|
UniProtKB:A4UU31
|
417 | ||||
|
UniProtKB:A0A8M9QIV0
|
490 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
map2k4b-201
(1)
|
Ensembl | 1,578 nt |
Interactions and Pathways
No data available
Plasmids
No data available