Gene
add2
- ID
- ZDB-GENE-080718-4
- Name
- adducin 2 (beta)
- Symbol
- add2 Nomenclature History
- Previous Names
-
- si:dkey-202n14.5 (1)
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to have actin filament binding activity; spectrin binding activity; and structural molecule activity. Predicted to be involved in actin filament bundle assembly and barbed-end actin filament capping. Predicted to localize to cytoskeleton; plasma membrane raft; and postsynaptic density. Human ortholog(s) of this gene implicated in IgA glomerulonephritis and hypertension. Is expressed in head. Orthologous to human ADD2 (adducin 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Aldolase class II Adducin subfamily | Class II aldolase/adducin N-terminal | Class II aldolase/adducin N-terminal domain superfamily |
|---|---|---|---|---|
|
UniProtKB:A0A8M9PKT7
|
568 | |||
|
UniProtKB:A0A8M6Z6F4
|
560 | |||
|
UniProtKB:A0A8M3B9E6
|
668 | |||
|
UniProtKB:F1QTE3
|
669 | |||
|
UniProtKB:A0A8M3B285
|
592 | |||
|
UniProtKB:F1RBS8
|
645 |
Interactions and Pathways
No data available
Plasmids
No data available