Gene
zeb2b
- ID
- ZDB-GENE-080717-1
- Name
- zinc finger E-box binding homeobox 2b
- Symbol
- zeb2b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have DNA binding activity and metal ion binding activity. Involved in several processes, including convergent extension; mesenchymal cell differentiation; and regionalization. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in Hirschsprung's disease and Mowat-Wilson syndrome. Is expressed in several structures, including digestive system; nervous system; presumptive mesoderm; tail bud; and vagal neural crest. Orthologous to human ZEB2 (zinc finger E-box binding homeobox 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Mowat-Wilson syndrome | Alliance | Mowat-Wilson syndrome | 235730 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001356 | Homeodomain |
| Domain | IPR008598 | Drought induced 19 protein type, zinc-binding domain |
| Domain | IPR013087 | Zinc finger C2H2-type |
| Family | IPR051574 | Zinc finger E-box-binding homeobox |
| Homologous_superfamily | IPR009057 | Homedomain-like superfamily |
| Homologous_superfamily | IPR036236 | Zinc finger C2H2 superfamily |
Domain Details Per Protein
| Protein | Length | Drought induced 19 protein type, zinc-binding domain | Homedomain-like superfamily | Homeodomain | Zinc finger C2H2 superfamily | Zinc finger C2H2-type | Zinc finger E-box-binding homeobox |
|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9QAF0
|
1219 | ||||||
|
UniProtKB:B0LVF0
|
1219 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available