Gene

mkxa

ID
ZDB-GENE-080513-1
Name
mohawk homeobox a
Symbol
mkxa Nomenclature History
Previous Names
  • irxl1 (1)
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Exhibits DNA binding activity. Involved in embryonic viscerocranium morphogenesis; myoblast differentiation; and negative regulation of transcription, DNA-templated. Predicted to localize to nucleus. Is expressed in several structures, including nervous system; neurocranial trabecula; notochord; pharyngeal arch; and pleuroperitoneal region. Orthologous to human MKX (mohawk homeobox).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
8 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mkxa Human Ortholog
No data available
Associated With mkxa Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR001356 Homeodomain
Domain IPR008422 KN homeodomain
Homologous_superfamily IPR009057 Homedomain-like superfamily
Domain Details Per Protein
Protein Length Homedomain-like superfamily Homeobox, conserved site Homeodomain KN homeodomain
UniProtKB:A5YC44 349
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA mkxa-201 (1) Ensembl 2,947 nt
ncRNA mkxa-002 (1) Ensembl 1,934 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations