Gene

myo18aa

ID

ZDB-GENE-080425-5

Name

myosin XVIIIAa

Symbol

myo18aa Nomenclature History

Previous Names

myo18b (1)
myo18l2

Type

protein_coding_gene

Location

Chr: 10 Mapping Details/Browsers

Description

Predicted to enable actin filament binding activity. Acts upstream of or within Golgi organization; cell-matrix adhesion; and muscle cell development. Predicted to be part of myosin II complex. Predicted to be active in cytoplasm and myosin filament. Is expressed in somite border. Orthologous to human MYO18A (myosin XVIIIA).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Cao et al., 2014

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 4 figures from Cao et al., 2014
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With myo18aa Human Ortholog

No data available

Associated With myo18aa Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Binding_site	IPR000048	IQ motif, EF-hand binding site
Domain	IPR001478	PDZ domain
Domain	IPR036064	Class XVIII myosin, motor domain
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily	IPR036034	PDZ superfamily
Homologous_superfamily	IPR036961	Kinesin motor domain superfamily

Domain Details Per Protein

Protein	Length	Class XVIII myosin, motor domain	IQ motif, EF-hand binding site	Kinesin motor domain superfamily	PDZ domain	PDZ superfamily	P-loop containing nucleoside triphosphate hydrolase
UniProtKB:A0A8M9QCN6 InterPro	2072
UniProtKB:A0A8M9QL86 InterPro	2508
UniProtKB:A0A8M3BDA6 InterPro	2493
UniProtKB:A0A8M9Q6N9 InterPro	2164
UniProtKB:A0A8M3B6I5 InterPro	2439
UniProtKB:A0A8M3AX53 InterPro	2504
UniProtKB:A0A8M9PUB6 InterPro	2484
UniProtKB:A0A8M9QH80 InterPro	2486
UniProtKB:A0A8M3AX31 InterPro	2087

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	myo18aa-201 (1) Ensembl	Ensembl		7,287 nt	Select Tool ZFIN BLAST
mRNA	myo18aa-202 (1) Ensembl	Ensembl		8,585 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations