Gene

nfic

ID

ZDB-GENE-080305-2

Name

nuclear factor I/C

Symbol

nfic Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 8 Mapping Details/Browsers

Description

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within DNA replication and regulation of DNA-templated transcription. Predicted to be active in nucleus. Is expressed in telencephalon. Orthologous to human NFIC (nuclear factor I C).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Diotel et al., 2015

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With nfic Human Ortholog

No data available

Associated With nfic Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR019739	CTF transcription factor/nuclear factor 1, conserved site
Domain	IPR003619	MAD homology 1, Dwarfin-type
Domain	IPR019548	CTF transcription factor/nuclear factor 1, N-terminal
Domain	IPR020604	CTF transcription factor/nuclear factor 1, DNA-binding domain
Family	IPR000647	CTF transcription factor/nuclear factor 1

Domain Details Per Protein

Protein	Length	CTF transcription factor/nuclear factor 1	CTF transcription factor/nuclear factor 1, conserved site	CTF transcription factor/nuclear factor 1, DNA-binding domain	CTF transcription factor/nuclear factor 1, N-terminal	MAD homology 1, Dwarfin-type
UniProtKB:A0A8M9Q3U5 InterPro	432
UniProtKB:A0A8M9QE35 InterPro	506
UniProtKB:A0A8M9QA09 InterPro	530
UniProtKB:A0A8M9Q2P0 InterPro	505
UniProtKB:A0A8M3B4V2 InterPro	521

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	nfic-201 (1) Ensembl	Ensembl	1,563 nt	Select Tool ZFIN BLAST
mRNA	nfic-202 (1) Ensembl	Ensembl	435 nt	Select Tool ZFIN BLAST
mRNA	nfic-203 (1) Ensembl	Ensembl	1,725 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations