Gene

sigirr

ID

ZDB-GENE-080303-3

Name

single immunoglobulin and toll-interleukin 1 receptor (TIR) domain

Symbol

sigirr Nomenclature History

Previous Names

sc:d148

Type

protein_coding_gene

Location

Chr: 25 Mapping Details/Browsers

Description

Involved in negative regulation of inflammatory response. Localizes to cell surface. Is expressed in brain; gill; integument; liver; and pleuroperitoneal region. Orthologous to human SIGIRR (single Ig and TIR domain containing).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

8 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

cssl:d148 (10 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With sigirr Human Ortholog

No data available

Associated With sigirr Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000157	Toll/interleukin-1 receptor homology (TIR) domain
Domain	IPR007110	Immunoglobulin-like domain
Family	IPR015621	Interleukin-1 receptor family
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR035897	Toll/interleukin-1 receptor homology (TIR) domain superfamily
Homologous_superfamily	IPR036179	Immunoglobulin-like domain superfamily