Gene
cers3b
- ID
- ZDB-GENE-080220-32
- Name
- ceramide synthase 3b
- Symbol
- cers3b Nomenclature History
- Previous Names
-
- cers3
- zgc:171494
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to have sphingosine N-acyltransferase activity. Predicted to be involved in ceramide biosynthetic process. Predicted to localize to endoplasmic reticulum. Is expressed in several structures, including digestive system; otic placode; otic vesicle; pectoral fin; and pronephric duct. Human ortholog(s) of this gene implicated in autosomal recessive congenital ichthyosis 9. Orthologous to human CERS3 (ceramide synthase 3).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
autosomal recessive congenital ichthyosis 9 | Alliance | Ichthyosis, congenital, autosomal recessive 9 | 615023 |
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | Homedomain-like superfamily | Homeodomain | Sphingosine N-acyltransferase Lag1/Lac1-like | TRAM/LAG1/CLN8 homology domain |
---|---|---|---|---|---|
UniProtKB:A8WFT1
|
351 | ||||
UniProtKB:A0A8M2B5K0
|
349 | ||||
UniProtKB:A0A8M9PF77
|
183 | ||||
UniProtKB:A0A8M2B5Y1
|
366 |
Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
aberrant processed transcript |
cers3b-202
(1)
|
Ensembl | 1,108 nt | ||
mRNA |
cers3b-201
(1)
|
Ensembl | 1,598 nt |
Interactions and Pathways
No data available
Plasmids
No data available