Gene

ca4a

ID
ZDB-GENE-080204-85
Name
carbonic anhydrase IV a
Symbol
ca4a Nomenclature History
Previous Names
  • zCA4a (1)
  • zgc:171842
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have carbonate dehydratase activity and zinc ion binding activity. Predicted to localize to anchored component of membrane; integral component of membrane; and plasma membrane. Human ortholog(s) of this gene implicated in retinitis pigmentosa and retinitis pigmentosa 17. Is expressed in brain; eye; heart; muscle; and pleuroperitoneal region. Orthologous to human CA4 (carbonic anhydrase 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ca4a Human Ortholog
No data available
Associated With ca4a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018338 Carbonic anhydrase, alpha-class, conserved site
Domain IPR001148 Alpha carbonic anhydrase domain
Family IPR023561 Carbonic anhydrase, alpha-class
Family IPR041874 Carbonic anhydrase, CA4/CA15
Homologous_superfamily IPR036398 Alpha carbonic anhydrase domain superfamily
Domain Details Per Protein
Protein Length Alpha carbonic anhydrase domain Alpha carbonic anhydrase domain superfamily Carbonic anhydrase, alpha-class Carbonic anhydrase, alpha-class, conserved site Carbonic anhydrase, CA4/CA15
UniProtKB:A9JSU9 306
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA ca4a-201 (1) Ensembl 2,294 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations