Gene
chst3b
- ID
- ZDB-GENE-080204-33
- Name
- carbohydrate (chondroitin 6) sulfotransferase 3b
- Symbol
- chst3b Nomenclature History
- Previous Names
-
- zgc:171664
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Description
- Predicted to enable cholesterol sulfotransferase activity; heparan sulfate 2-O-sulfotransferase activity; and heparan sulfate 6-O-sulfotransferase activity. Predicted to act upstream of or within carbohydrate metabolic process. Predicted to be located in Golgi membrane. Is expressed in pectoral fin and somite. Human ortholog(s) of this gene implicated in osteochondrodysplasia and spondyloepiphyseal dysplasia with congenital joint dislocations. Orthologous to human CHST3 (carbohydrate sulfotransferase 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Habicher et al., 2015
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| spondyloepiphyseal dysplasia with congenital joint dislocations | Alliance | Spondyloepiphyseal dysplasia with congenital joint dislocations | 143095 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Carbohydrate sulfotransferase | Gal/GlcNAc/GalNAc Sulfotransferase | P-loop containing nucleoside triphosphate hydrolase | Sulfotransferase domain |
|---|---|---|---|---|---|
|
UniProtKB:A8WFU7
|
419 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
chst3b-201
(1)
|
Ensembl | 3,225 nt |
Interactions and Pathways
No data available
Plasmids
No data available