Gene
il2rb
- ID
- ZDB-GENE-080108-2
- Name
- interleukin 2 receptor, beta
- Symbol
- il2rb Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to enable cytokine receptor activity. Predicted to be involved in cytokine-mediated signaling pathway and immunoglobulin mediated immune response. Predicted to be located in plasma membrane. Predicted to be active in external side of plasma membrane. Is expressed in head kidney. Human ortholog(s) of this gene implicated in asthma; immunodeficiency 63; myasthenia gravis; and visceral leishmaniasis. Orthologous to human IL2RB (interleukin 2 receptor subunit beta).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| immunodeficiency 63 | Alliance | Immunodeficiency 63 with lymphoproliferation and autoimmunity | 618495 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Fibronectin type III superfamily | Immunoglobulin-like fold | Interleukin-2 receptor subunit beta, N-terminal | Short hematopoietin receptor, family 1, conserved site |
|---|---|---|---|---|---|
|
UniProtKB:A8WH92
|
503 | ||||
|
UniProtKB:A0A8M2BIX1
|
541 |
Interactions and Pathways
No data available
Plasmids
No data available