Gene
mst1rb
- ID
- ZDB-GENE-071218-3
- Name
- macrophage stimulating 1 receptor b
- Symbol
- mst1rb Nomenclature History
- Previous Names
-
- prgfr3
- ron2 (1)
- Type
- protein_coding_gene
- Location
- Chr: 11 Mapping Details/Browsers
- Description
- Predicted to enable transmembrane receptor protein tyrosine kinase activity. Acts upstream of or within bone mineralization. Predicted to be located in membrane. Predicted to be part of receptor complex. Predicted to be active in plasma membrane. Is expressed in corpuscles of Stannius and pronephros. Human ortholog(s) of this gene implicated in nasopharynx carcinoma. Orthologous to human MST1R (macrophage stimulating 1 receptor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Huitema et al., 2012
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| {Nasopharyngeal carcinoma, susceptibility to, 3} | 617075 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008266 | Tyrosine-protein kinase, active site |
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR001245 | Serine-threonine/tyrosine-protein kinase, catalytic domain |
| Domain | IPR001627 | Sema domain |
| Domain | IPR002909 | IPT domain |
| Domain | IPR016201 | PSI domain |
| Domain | IPR020635 | Tyrosine-protein kinase, catalytic domain |
| Family | IPR016244 | Tyrosine-protein kinase, HGF/MSP receptor |
| Family | IPR050122 | Receptor Tyrosine Kinase |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR014756 | Immunoglobulin E-set |
| Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
| Homologous_superfamily | IPR036352 | Sema domain superfamily |
| Repeat | IPR002165 | Plexin repeat |
Domain Details Per Protein
| Protein | Length | Immunoglobulin E-set | Immunoglobulin-like fold | IPT domain | Plexin repeat | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | PSI domain | Receptor Tyrosine Kinase | Sema domain | Sema domain superfamily | Serine-threonine/tyrosine-protein kinase, catalytic domain | Tyrosine-protein kinase, active site | Tyrosine-protein kinase, catalytic domain | Tyrosine-protein kinase, HGF/MSP receptor | WD40/YVTN repeat-like-containing domain superfamily |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9QI71
|
1374 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
mst1rb-201
(1)
|
Ensembl | 4,140 nt | ||
| mRNA |
mst1rb-202
(1)
|
Ensembl | 4,131 nt |
Interactions and Pathways
No data available
Plasmids
No data available