Gene
itgb8
- ID
- ZDB-GENE-071213-3
- Name
- integrin, beta 8
- Symbol
- itgb8 Nomenclature History
- Previous Names
-
- si:ch1073-83d9.2
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to enable integrin binding activity. Acts upstream of or within angiogenesis and endothelial cell proliferation. Predicted to be located in membrane. Predicted to be part of integrin complex. Predicted to be active in cell surface and focal adhesion. Is expressed in head. Orthologous to human ITGB8 (integrin subunit beta 8).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Liu et al., 2012
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR002369 | Integrin beta subunit, VWA domain |
| Domain | IPR012896 | Integrin beta subunit, tail |
| Domain | IPR013111 | EGF-like domain, extracellular |
| Family | IPR015812 | Integrin beta subunit |
| Homologous_superfamily | IPR032695 | Integrin domain superfamily |
| Homologous_superfamily | IPR036349 | Integrin beta tail domain superfamily |
| Homologous_superfamily | IPR036465 | von Willebrand factor A-like domain superfamily |
Domain Details Per Protein
| Protein | Length | EGF-like domain, extracellular | Integrin beta subunit | Integrin beta subunit, tail | Integrin beta subunit, VWA domain | Integrin beta tail domain superfamily | Integrin domain superfamily | von Willebrand factor A-like domain superfamily |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9PB88
|
719 |
Interactions and Pathways
No data available
Plasmids
No data available