Gene

atg12

ID

ZDB-GENE-071205-7

Name

ATG12 autophagy related 12 homolog (S. cerevisiae)

Symbol

atg12 Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Description

Predicted to be involved in several processes, including C-terminal protein lipidation; autophagosome assembly; and autophagy of mitochondrion. Predicted to localize to Atg12-Atg5-Atg16 complex and phagophore assembly site membrane. Is expressed in brain; liver; and muscle. Orthologous to human ATG12 (autophagy related 12).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

14 figures from 11 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Lu et al., 2019
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With atg12 Human Ortholog

No data available

Associated With atg12 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Family	IPR007242	Ubiquitin-like protein Atg12
Homologous_superfamily	IPR029071	Ubiquitin-like domain superfamily

Domain Details Per Protein

Protein	Length	Ubiquitin-like domain superfamily	Ubiquitin-like protein Atg12
UniProtKB:F5ATB4 InterPro	120

Transcripts

Genome Browsers

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	atg12-201 (1) Ensembl	Ensembl		584 nt	Select Tool
mRNA	atg12-202 (1) Ensembl	Ensembl		668 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations