Gene
htr1aa
- ID
- ZDB-GENE-071203-1
- Name
- 5-hydroxytryptamine (serotonin) receptor 1A a
- Symbol
- htr1aa Nomenclature History
- Previous Names
-
- htr1a (1)
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to have G protein-coupled serotonin receptor activity and serotonin binding activity. Predicted to be involved in adenylate cyclase-inhibiting serotonin receptor signaling pathway and chemical synaptic transmission. Predicted to localize to dendrite and integral component of plasma membrane. Human ortholog(s) of this gene implicated in anxiety disorder; mental depression; and panic disorder. Is expressed in nervous system and pharynx. Orthologous to human HTR1A (5-hydroxytryptamine receptor 1A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 20 figures from 13 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| vesicoureteral reflux | Alliance | ?Periodic fever, menstrual cycle dependent | 614674 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | 5-Hydroxytryptamine 1A receptor | 5-hydroxytryptamine receptor family | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like |
|---|---|---|---|---|---|
|
UniProtKB:B0S6X1
|
398 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
htr1aa-201
(1)
|
Ensembl | 1,786 nt |
Interactions and Pathways
No data available
Plasmids
No data available