Gene
ankk1
- ID
- ZDB-GENE-071015-4
- Name
- ankyrin repeat and kinase domain containing 1
- Symbol
- ankk1 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to enable ATP binding activity and protein serine/threonine kinase activity. Acts upstream of or within habituation and startle response. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in several diseases, including alcohol dependence; alcohol use disorder; alexithymia; drug dependence (multiple); and mild cognitive impairment. Orthologous to human ANKK1 (ankyrin repeat and kinase domain containing 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Leggieri et al., 2022
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Leggieri et al., 2022
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR001245 | Serine-threonine/tyrosine-protein kinase, catalytic domain |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
| Homologous_superfamily | IPR036770 | Ankyrin repeat-containing domain superfamily |
| Repeat | IPR002110 | Ankyrin repeat |
Domain Details Per Protein
| Protein | Length | Ankyrin repeat | Ankyrin repeat-containing domain superfamily | Protein kinase domain | Protein kinase-like domain superfamily | Serine-threonine/tyrosine-protein kinase, catalytic domain |
|---|---|---|---|---|---|---|
|
UniProtKB:B3DHM4
|
733 |
Interactions and Pathways
No data available
Plasmids
No data available