Gene

hrh2b

ID

ZDB-GENE-070928-20

Name

histamine receptor H2b

Symbol

hrh2b Nomenclature History

Previous Names

si:dkey-179g5.13
zgc:171684 (1)

Type

protein_coding_gene

Location

Chr: 10 Mapping Details/Browsers

Description

Predicted to have G protein-coupled serotonin receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger and chemical synaptic transmission. Predicted to localize to dendrite and integral component of plasma membrane. Orthologous to human HRH2 (histamine receptor H2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Oprişoreanu et al., 2023

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With hrh2b Human Ortholog

No data available

Associated With hrh2b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR017452	GPCR, rhodopsin-like, 7TM
Family	IPR000276	G protein-coupled receptor, rhodopsin-like

Domain Details Per Protein

Protein	Length	GPCR, rhodopsin-like, 7TM	G protein-coupled receptor, rhodopsin-like
UniProtKB:A7MBV0 InterPro	335

Transcripts

Genome Browsers

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	hrh2b-201 (1) Ensembl	Ensembl		1,679 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations