Gene

kcnab1b

ID

ZDB-GENE-070912-690

Name

potassium voltage-gated channel subfamily A regulatory beta subunit 1b

Symbol

kcnab1b Nomenclature History

Previous Names

si:dkeyp-94h10.1

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Description

Predicted to have voltage-gated potassium channel activity. Predicted to be involved in potassium ion transport and transmembrane transport. Predicted to localize to cytoplasm and integral component of membrane. Human ortholog(s) of this gene implicated in temporal lobe epilepsy. Is expressed in female organism. Orthologous to human KCNAB1 (potassium voltage-gated channel subfamily A member regulatory beta subunit 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With kcnab1b Human Ortholog

No data available

Associated With kcnab1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR023210	NADP-dependent oxidoreductase domain
Family	IPR005399	Potassium channel, voltage-dependent, beta subunit, KCNAB-related
Family	IPR005400	Potassium channel, voltage-dependent, beta subunit, KCNAB1
Family	IPR005983	Potassium channel, voltage-dependent, beta subunit, KCNAB
Homologous_superfamily	IPR036812	NADP-dependent oxidoreductase domain superfamily

Domain Details Per Protein

Protein	Length	NADP-dependent oxidoreductase domain	NADP-dependent oxidoreductase domain superfamily	Potassium channel, voltage-dependent, beta subunit, KCNAB	Potassium channel, voltage-dependent, beta subunit, KCNAB1	Potassium channel, voltage-dependent, beta subunit, KCNAB-related
UniProtKB:A0A8M9PRF1 InterPro	399
UniProtKB:A0A8M3AQ10 InterPro	413
UniProtKB:A0A8M9PXK3 InterPro	348

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	kcnab1b-201 (1) Ensembl	Ensembl		1,128 nt	Select Tool ZFIN BLAST
mRNA	kcnab1b-202 (1) Ensembl	Ensembl		2,034 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations