Gene
dcaf8
- ID
- ZDB-GENE-070912-578
- Name
- DDB1 and CUL4 associated factor 8
- Symbol
- dcaf8 Nomenclature History
- Previous Names
-
- si:dkey-75g22.6 (1)
- si:rp71-1g18.15
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to localize to Cul4-RING E3 ubiquitin ligase complex and cytoplasm. Human ortholog(s) of this gene implicated in giant axonal neuropathy 2. Orthologous to human DCAF8 (DDB1 and CUL4 associated factor 8).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Charlton-Perkins et al., 2019
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| giant axonal neuropathy 2 | Alliance | ?Giant axonal neuropathy 2, autosomal dominant | 610100 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | DDB1- and CUL4-associated factor 8-like | WD40 repeat | WD40-repeat-containing domain superfamily | WD40/YVTN repeat-like-containing domain superfamily |
|---|---|---|---|---|---|
|
UniProtKB:F1QF18
|
607 |
Interactions and Pathways
No data available
Plasmids
No data available