Gene
myo10
- ID
- ZDB-GENE-070912-277
- Name
- myosin X
- Symbol
- myo10 Nomenclature History
- Previous Names
-
- myo10b (1)
- myo10l2
- si:ch211-283p23.2
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to enable actin filament binding activity; phosphatidylinositol-3,4,5-trisphosphate binding activity; and plus-end directed microfilament motor activity. Predicted to be involved in cytoskeleton-dependent intracellular transport; regulation of cell shape; and regulation of filopodium assembly. Predicted to act upstream of or within signal transduction. Predicted to be located in cytoplasm and cytoskeleton. Predicted to be part of myosin complex. Predicted to be active in filopodium. Is expressed in midbrain hindbrain boundary; otic vesicle; and rhombomere. Orthologous to human MYO10 (myosin X).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from Sittaramane et al., 2008
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Binding_site | IPR000048 | IQ motif, EF-hand binding site |
| Domain | IPR000159 | Ras-associating domain |
| Domain | IPR000299 | FERM domain |
| Domain | IPR000857 | MyTH4 domain |
| Domain | IPR001609 | Myosin head, motor domain-like |
| Domain | IPR001849 | Pleckstrin homology domain |
| Domain | IPR019748 | FERM central domain |
| Domain | IPR019749 | Band 4.1 domain |
| Domain | IPR031971 | Unconventional myosin-X, coiled coil domain |
| Domain | IPR036124 | Class X myosin, motor domain |
| Domain | IPR040640 | Myosin X, N-terminal SH3 domain |
| Domain | IPR041797 | Myosin X, FERM domain C-lobe |
| Family | IPR051724 | Actin-based Motor Myosin |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR014352 | FERM/acyl-CoA-binding protein superfamily |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR035963 | FERM superfamily, second domain |
| Homologous_superfamily | IPR036961 | Kinesin motor domain superfamily |
| Homologous_superfamily | IPR038185 | MyTH4 domain superfamily |
Domain Details Per Protein
| Protein | Length | Actin-based Motor Myosin | Band 4.1 domain | Class X myosin, motor domain | FERM/acyl-CoA-binding protein superfamily | FERM central domain | FERM domain | FERM superfamily, second domain | IQ motif, EF-hand binding site | Kinesin motor domain superfamily | Myosin head, motor domain-like | Myosin X, FERM domain C-lobe | Myosin X, N-terminal SH3 domain | MyTH4 domain | MyTH4 domain superfamily | PH-like domain superfamily | Pleckstrin homology domain | P-loop containing nucleoside triphosphate hydrolase | Ras-associating domain | Unconventional myosin-X, coiled coil domain |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9P844
|
1425 | |||||||||||||||||||
|
UniProtKB:A0A8M6Z236
|
1425 | |||||||||||||||||||
|
UniProtKB:A0A8M9PXE2
|
2069 | |||||||||||||||||||
|
UniProtKB:B0S541
|
2069 | |||||||||||||||||||
|
UniProtKB:A0A8M3B0G0
|
2013 |
Interactions and Pathways
No data available
Plasmids
No data available