Gene

satb2

ID

ZDB-GENE-070912-212

Name

SATB homeobox 2

Symbol

satb2 Nomenclature History

Previous Names

si:ch211-223c6.1

Type

protein_coding_gene

Location

Chr: 9 Mapping Details/Browsers

Description

Predicted to have RNA polymerase II regulatory region sequence-specific DNA binding activity. Involved in epiboly involved in gastrulation with mouth forming second. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in chromosome 2q32-q33 deletion syndrome. Is expressed in fin; head; nervous system; pharyngeal endoderm; and pronephric duct. Orthologous to human SATB2 (SATB homeobox 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

15 figures from 7 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 3 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With satb2 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
SATB2-associated syndrome	Alliance	Glass syndrome	612313

Associated With satb2 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001356	Homeodomain
Domain	IPR003350	CUT domain
Domain	IPR032355	SATB, CUT1-like DNA-binding domain
Domain	IPR032392	SATB, ubiquitin-like oligomerisation domain
Family	IPR039673	DNA-binding protein SATB1/SATB2
Homologous_superfamily	IPR009057	Homedomain-like superfamily
Homologous_superfamily	IPR010982	Lambda repressor-like, DNA-binding domain superfamily
Homologous_superfamily	IPR038216	SATB, CUTL domain superfamily
Homologous_superfamily	IPR038224	SATB, ULD domain superfamily