Gene
adap2
- ID
- ZDB-GENE-070912-21
- Name
- ArfGAP with dual PH domains 2
- Symbol
- adap2 Nomenclature History
- Previous Names
-
- si:ch211-11k18.11 (1)
- si:ch73-33i10.5
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to have GTPase activator activity; metal ion binding activity; and phosphatidylinositol bisphosphate binding activity. Involved in atrioventricular valve development; heart jogging; and heart looping. Predicted to localize to intracellular membrane-bounded organelle and plasma membrane. Is expressed in several structures, including digestive system; gonad; head; heart; and skeletal muscle. Orthologous to human ADAP2 (ArfGAP with dual PH domains 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 6 figures from Venturin et al., 2014
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001164 | Arf GTPase activating protein |
| Domain | IPR001849 | Pleckstrin homology domain |
| Domain | IPR037849 | ADAP, PH domain 1 |
| Domain | IPR037851 | ADAP, PH domain 2 |
| Family | IPR052589 | Arf-GAP with dual PH domain-containing protein |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR037278 | ARFGAP/RecO-like zinc finger |
| Homologous_superfamily | IPR038508 | ArfGAP domain superfamily |
Domain Details Per Protein
| Protein | Length | ADAP, PH domain 1 | ADAP, PH domain 2 | ArfGAP domain superfamily | ARFGAP/RecO-like zinc finger | Arf-GAP with dual PH domain-containing protein | Arf GTPase activating protein | PH-like domain superfamily | Pleckstrin homology domain |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9Q881
|
418 | ||||||||
|
UniProtKB:E9QE78
|
378 |
Interactions and Pathways
No data available
Plasmids
No data available