Gene
loxl3a
- ID
- ZDB-GENE-070818-2
- Name
- lysyl oxidase-like 3a
- Symbol
- loxl3a Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to have fibronectin binding activity and protein-lysine 6-oxidase activity. Predicted to be involved in several processes, including collagen fibril organization; fibronectin fibril organization; and negative regulation of T-helper 17 cell lineage commitment. Predicted to localize to cytoplasm; extracellular space; and nucleus. Is expressed in head mesenchyme; mesenchyme; and notochord. Orthologous to human LOXL3 (lysyl oxidase like 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Myopia 28, autosomal recessive | 619781 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Lysyl oxidase | Lysyl oxidase, conserved site | Lysyl oxidase-like protein | SRCR domain | SRCR-like domain superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:X1WBP7
|
||||||
|
UniProtKB:F1RD85
|
739 | |||||
|
UniProtKB:A0A5H1ZRI5
|
791 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
loxl3a-201
(1)
|
Ensembl | 2,373 nt | ||
| mRNA |
loxl3a-202
(1)
|
Ensembl | 2,529 nt | ||
| mRNA |
loxl3a-203
(1)
|
Ensembl | 2,220 nt |
Interactions and Pathways
No data available
Plasmids
No data available