Gene
plk2b
- ID
- ZDB-GENE-070720-17
- Name
- polo-like kinase 2b (Drosophila)
- Symbol
- plk2b Nomenclature History
- Previous Names
-
- plk2
- zgc:165644 (1)
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to have protein serine/threonine kinase activity. Involved in sprouting angiogenesis. Predicted to localize to cytoplasm; microtubule cytoskeleton; and nucleus. Is expressed in endothelial cell and vasculature. Orthologous to human PLK2 (polo like kinase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Yang et al., 2015
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR000959 | POLO box domain |
| Domain | IPR033695 | Second polo-box domain |
| Domain | IPR033701 | First polo-box domain |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
| Homologous_superfamily | IPR036947 | POLO box domain superfamily |
Domain Details Per Protein
| Protein | Length | First polo-box domain | POLO box domain | POLO box domain superfamily | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Second polo-box domain | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A6H8T5
|
657 |
Interactions and Pathways
No data available
Plasmids
No data available