Gene
amer1
- ID
- ZDB-GENE-070719-2
- Name
- APC membrane recruitment protein 1
- Symbol
- amer1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to have beta-catenin binding activity and phosphatidylinositol-4,5-bisphosphate binding activity. Involved in negative regulation of Wnt signaling pathway. Predicted to localize to plasma membrane. Human ortholog(s) of this gene implicated in osteopathia striata with cranial sclerosis. Is expressed in head. Orthologous to human AMER1 (APC membrane recruitment protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| osteopathia striata with cranial sclerosis | Alliance | Osteopathia striata with cranial sclerosis | 300373 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR019003 | APC membrane recruitment protein |
Domain Details Per Protein
| Protein | Length | APC membrane recruitment protein |
|---|---|---|
|
UniProtKB:A0A2R8RN23
|
953 | |
|
UniProtKB:F1RDM5
|
930 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available