Gene

rfx5

ID
ZDB-GENE-070717-3
Name
regulatory factor X, 5
Symbol
rfx5 Nomenclature History
Previous Names
  • si:ch211-210h11.13
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to enable K48-linked deubiquitinase activity and cysteine-type carboxypeptidase activity. Predicted to act upstream of or within regulation of DNA-templated transcription. Human ortholog(s) of this gene implicated in severe combined immunodeficiency. Orthologous to human RFX5 (regulatory factor X5).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With rfx5 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
MHC class II deficiency 3 620816
?MHC class II deficiency 5 620818
Associated With rfx5 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003150 DNA-binding RFX-type winged-helix domain
Family IPR039779 RFX-like DNA-binding protein
Homologous_superfamily IPR036388 Winged helix-like DNA-binding domain superfamily
Homologous_superfamily IPR036390 Winged helix DNA-binding domain superfamily
Domain Details Per Protein
Protein Additional Resources Length DNA-binding RFX-type winged-helix domain RFX-like DNA-binding protein Winged helix DNA-binding domain superfamily Winged helix-like DNA-binding domain superfamily
UniProtKB:A0A8M2B678 InterPro 590
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA rfx5-201 (1)
Ensembl
Ensembl 5,783 nt
ZFIN BLAST
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations
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