Gene

ccn2b

ID

ZDB-GENE-070705-82

Name

cellular communication network factor 2b

Symbol

ccn2b Nomenclature History

Previous Names

ctgfb
si:ch211-173b8.2
zCTGF-c19 (1)

Type

protein_coding_gene

Location

Chr: 19 Mapping Details/Browsers

Description

Predicted to have heparin binding activity and integrin binding activity. Predicted to be involved in cell adhesion; negative regulation of cell death; and signal transduction. Predicted to localize to extracellular matrix. Is expressed in axis; head; neural plate; notochord posterior region; and trunk. Orthologous to human CCN2 (cellular communication network factor 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

8 figures from 6 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ccn2b Human Ortholog

No data available

Associated With ccn2b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR017891	Insulin-like growth factor binding protein, N-terminal, Cys-rich conserved site
Domain	IPR000867	Insulin-like growth factor-binding protein, IGFBP
Domain	IPR001007	VWFC domain
Domain	IPR006207	Cystine knot, C-terminal
Domain	IPR006208	Glycoprotein hormone subunit beta
Domain	IPR043973	CCN, TSP1 domain
Family	IPR012395	IGFBP-related, CNN
Family	IPR050941	Cellular Communication Network Factor
Homologous_superfamily	IPR009030	Growth factor receptor cysteine-rich domain superfamily
Homologous_superfamily	IPR036383	Thrombospondin type-1 (TSP1) repeat superfamily
Repeat	IPR000884	Thrombospondin type-1 (TSP1) repeat