Gene
rragd
- ID
- ZDB-GENE-070620-6
- Name
- ras-related GTP binding D
- Symbol
- rragd Nomenclature History
- Previous Names
-
- zgc:162165
- Type
- protein_coding_gene
- Location
- Chr: 17 Mapping Details/Browsers
- Description
- Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in cellular response to starvation; negative regulation of autophagy; and positive regulation of TORC1 signaling. Predicted to be located in cytoplasm; endomembrane system; and membrane. Predicted to be part of Gtr1-Gtr2 GTPase complex. Predicted to be active in lysosome and nucleus. Human ortholog(s) of this gene implicated in renal hypomagnesemia 7, with or without dilated cardiomyopathy. Orthologous to human RRAGD (Ras related GTP binding D).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Ding et al., 2011
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| renal hypomagnesemia 7, with or without dilated cardiomyopathy | Alliance | Hypomagnesemia 7, renal, with or without dilated cardiomyopathy | 620152 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Gtr1/RagA G protein | P-loop containing nucleoside triphosphate hydrolase | RagC/D |
|---|---|---|---|---|
|
UniProtKB:A0A8M9PNV5
|
252 | |||
|
UniProtKB:F1QIB5
|
394 |
Interactions and Pathways
No data available
Plasmids
No data available