Gene
f2rl1.2
- ID
- ZDB-GENE-070615-24
- Name
- coagulation factor II (thrombin) receptor-like 1, tandem duplicate 2
- Symbol
- f2rl1.2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Enables proteinase-activated receptor activity. Acts upstream of or within with a negative effect on cell population proliferation. Acts upstream of or within morphogenesis of an epithelium. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in digestive system; notochord; otic vesicle; pronephric duct; and thrombocyte. Human ortholog(s) of this gene implicated in asthma; chronic obstructive pulmonary disease; and respiratory allergy. Orthologous to human F2RL1 (F2R like trypsin receptor 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Schepis et al., 2018
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | GPCR, rhodopsin-like, 7TM | G protein-coupled receptor, rhodopsin-like | Protease-activated receptor | Protease-activated receptor 2 |
|---|---|---|---|---|---|
|
UniProtKB:I3IRY7
|
390 | ||||
|
UniProtKB:A5PLC2
|
389 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
f2rl1.2-201
(1)
|
Ensembl | 1,486 nt | ||
| mRNA |
f2rl1.2-202
(1)
|
Ensembl | 1,493 nt |
Interactions and Pathways
No data available
Plasmids
No data available