Gene
casp8l1
- ID
- ZDB-GENE-070608-1
- Name
- caspase 8, apoptosis-related cysteine peptidase, like 1
- Symbol
- casp8l1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to enable cysteine-type endopeptidase activity. Predicted to be involved in apoptotic process and positive regulation of neuron apoptotic process. Predicted to act upstream of or within proteolysis. Predicted to be part of CD95 death-inducing signaling complex. Predicted to be active in cytoplasm.
- Genome Resources
-
- Alliance (1)
- Gene:100049706 (1)
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Spead et al., 2018
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR033139 | Peptidase family C14A, cysteine active site |
| Domain | IPR001309 | Peptidase C14, p20 domain |
| Domain | IPR002138 | Peptidase C14, caspase non-catalytic subunit p10 |
| Domain | IPR011600 | Peptidase C14, caspase domain |
| Domain | IPR015917 | Peptidase C14A, caspase catalytic domain |
| Homologous_superfamily | IPR029030 | Caspase-like domain superfamily |
Domain Details Per Protein
| Protein | Length | Caspase-like domain superfamily | Peptidase C14A, caspase catalytic domain | Peptidase C14, caspase domain | Peptidase C14, caspase non-catalytic subunit p10 | Peptidase C14, p20 domain | Peptidase family C14A, cysteine active site |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q0PKX1
|
330 | ||||||
|
UniProtKB:A0A2U9DQL0
|
330 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance