Gene

trpm1b

ID

ZDB-GENE-070424-31

Name

transient receptor potential cation channel, subfamily M, member 1b

Symbol

trpm1b Nomenclature History

Previous Names

trpm1a (1)
zgc:162329

Type

protein_coding_gene

Location

Chr: 25 Mapping Details/Browsers

Description

Predicted to enable calcium channel activity. Predicted to be involved in monoatomic cation transmembrane transport. Predicted to act upstream of or within several processes, including G protein-coupled glutamate receptor signaling pathway; cellular response to light stimulus; and protein tetramerization. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in melanoblast; neural crest cell; and retina. Human ortholog(s) of this gene implicated in congenital stationary night blindness and congenital stationary night blindness 1C. Orthologous to human TRPM1 (transient receptor potential cation channel subfamily M member 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With trpm1b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
congenital stationary night blindness 1C	Alliance	Night blindness, congenital stationary (complete), 1C, autosomal recessive	613216

Associated With trpm1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR041491	TRPM, SLOG domain
Family	IPR050927	Transient receptor potential cation channel M

Domain Details Per Protein

Protein	Length	Transient receptor potential cation channel M	TRPM, SLOG domain
UniProtKB:A0A8M9PV08 InterPro	410
UniProtKB:A0A8M9P6H0 InterPro	343
UniProtKB:A3KNP8 InterPro	297

Transcripts

Genome Browsers

NCBI

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	trpm1b-201 (1) Ensembl	Ensembl		1,678 nt	Select Tool ZFIN BLAST
mRNA	trpm1b-202 (1) Ensembl	Ensembl		4,785 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations