Gene
pmvk
- ID
- ZDB-GENE-070410-91
- Name
- phosphomevalonate kinase
- Symbol
- pmvk Nomenclature History
- Previous Names
-
- zgc:162701
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to enable phosphomevalonate kinase activity. Predicted to be involved in cholesterol biosynthetic process and isopentenyl diphosphate biosynthetic process, mevalonate pathway. Predicted to act upstream of or within cholesterol metabolic process; phosphorylation; and sterol biosynthetic process. Predicted to be located in cytosol. Is expressed in female organism and male organism. Human ortholog(s) of this gene implicated in porokeratosis. Orthologous to human PMVK (phosphomevalonate kinase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Pradhan et al., 2018
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| porokeratosis | Alliance | Porokeratosis 1, multiple types | 175800 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Higher eukaryotic phosphomevalonate kinase | P-loop containing nucleoside triphosphate hydrolase |
|---|---|---|---|
|
UniProtKB:A4IGD4
|
199 |
Interactions and Pathways
No data available
Plasmids
No data available