Gene
hal
- ID
- ZDB-GENE-070410-5
- Name
- histidine ammonia-lyase
- Symbol
- hal Nomenclature History
- Previous Names
-
- zgc:136980
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to enable histidine ammonia-lyase activity. Acts upstream of or within hematopoietic stem cell differentiation. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in histidinemia. Orthologous to human HAL (histidine ammonia-lyase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Han et al., 2016
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| histidinemia | Alliance | [Histidinemia] | 235800 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR022313 | Phenylalanine/histidine ammonia-lyases, active site |
| Domain | IPR021922 | Par3/HAL, N-terminal |
| Family | IPR001106 | Aromatic amino acid lyase |
| Family | IPR005921 | Histidine ammonia-lyase |
| Homologous_superfamily | IPR008948 | L-Aspartase-like |
| Homologous_superfamily | IPR024083 | Fumarase/histidase, N-terminal |
Domain Details Per Protein
| Protein | Length | Aromatic amino acid lyase | Fumarase/histidase, N-terminal | Histidine ammonia-lyase | L-Aspartase-like | Par3/HAL, N-terminal | Phenylalanine/histidine ammonia-lyases, active site |
|---|---|---|---|---|---|---|---|
|
UniProtKB:A4FUP1
|
654 |
Interactions and Pathways
No data available
Plasmids
No data available