Gene
hal
- ID
- ZDB-GENE-070410-5
- Name
- histidine ammonia-lyase
- Symbol
- hal Nomenclature History
- Previous Names
-
- zgc:136980
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to have histidine ammonia-lyase activity. Involved in hematopoietic stem cell differentiation. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in histidinemia. Orthologous to human HAL (histidine ammonia-lyase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Han et al., 2016
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| histidinemia | Alliance | [Histidinemia] | 235800 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR022313 | Phenylalanine/histidine ammonia-lyases, active site |
| Domain | IPR021922 | Par3/HAL, N-terminal |
| Family | IPR001106 | Aromatic amino acid lyase |
| Family | IPR005921 | Histidine ammonia-lyase |
| Homologous_superfamily | IPR008948 | L-Aspartase-like |
| Homologous_superfamily | IPR024083 | Fumarase/histidase, N-terminal |
Domain Details Per Protein
| Protein | Length | Aromatic amino acid lyase | Fumarase/histidase, N-terminal | Histidine ammonia-lyase | L-Aspartase-like | Par3/HAL, N-terminal | Phenylalanine/histidine ammonia-lyases, active site |
|---|---|---|---|---|---|---|---|
|
UniProtKB:A4FUP1
|
654 |
Interactions and Pathways
No data available
Plasmids
No data available