Gene

hal

ID
ZDB-GENE-070410-5
Name
histidine ammonia-lyase
Symbol
hal Nomenclature History
Previous Names
  • zgc:136980
Type
protein_coding_gene
Location
Chr: 25 Mapping Details/Browsers
Description
Predicted to have histidine ammonia-lyase activity. Involved in hematopoietic stem cell differentiation. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in histidinemia. Orthologous to human HAL (histidine ammonia-lyase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Han et al., 2016
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With hal Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
histidinemia Alliance [Histidinemia] 235800
Associated With hal Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR022313 Phenylalanine/histidine ammonia-lyases, active site
Domain IPR021922 Par3/HAL, N-terminal
Family IPR001106 Aromatic amino acid lyase
Family IPR005921 Histidine ammonia-lyase
Homologous_superfamily IPR008948 L-Aspartase-like
Homologous_superfamily IPR024083 Fumarase/histidase, N-terminal
Domain Details Per Protein
Protein Length Aromatic amino acid lyase Fumarase/histidase, N-terminal Histidine ammonia-lyase L-Aspartase-like Par3/HAL, N-terminal Phenylalanine/histidine ammonia-lyases, active site
UniProtKB:A4FUP1 654
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA hal-201 (1) Ensembl 2,253 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations