Gene
mlycd
- ID
- ZDB-GENE-070410-120
- Name
- malonyl-CoA decarboxylase
- Symbol
- mlycd Nomenclature History
- Previous Names
-
- zgc:162977
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to have malonyl-CoA decarboxylase activity. Predicted to be involved in acetyl-CoA biosynthetic process; malonyl-CoA catabolic process; and positive regulation of fatty acid oxidation. Predicted to localize to mitochondrial matrix and peroxisomal matrix. Human ortholog(s) of this gene implicated in cardiomyopathy. Orthologous to human MLYCD (malonyl-CoA decarboxylase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Malonyl-CoA decarboxylase deficiency | 248360 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR007956 | Malonyl-CoA decarboxylase, C-terminal |
| Domain | IPR035372 | Malonyl-CoA decarboxylase, N-terminal |
| Family | IPR038917 | Malonyl-CoA decarboxylase |
| Homologous_superfamily | IPR038351 | Malonyl-CoA decarboxylase, N-terminal domain superfamily |
| Homologous_superfamily | IPR042303 | Malonyl-CoA decarboxylase, C-terminal catalytic domain superfamily |
Domain Details Per Protein
| Protein | Length | Malonyl-CoA decarboxylase | Malonyl-CoA decarboxylase, C-terminal | Malonyl-CoA decarboxylase, C-terminal catalytic domain superfamily | Malonyl-CoA decarboxylase, N-terminal | Malonyl-CoA decarboxylase, N-terminal domain superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:A3KP65
|
504 |
Interactions and Pathways
No data available
Plasmids
No data available