Gene

aopep

ID

ZDB-GENE-070410-115

Name

aminopeptidase O (putative)

Symbol

aopep Nomenclature History

Previous Names

cb974 (1)
wu:fa96d09
wu:fc79b08
zgc:162939

Type

protein_coding_gene

Location

Chr: 8 Mapping Details/Browsers

Description

Predicted to have metalloaminopeptidase activity and zinc ion binding activity. Predicted to localize to nucleolus. Is expressed in central nervous system; lateral line system; neural tube; pectoral fin; and tail bud. Orthologous to human AOPEP (aminopeptidase O (putative)).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

11 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

cb974 (6 images)
IMAGE:7162376 (6 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With aopep Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
dystonia 31	Alliance	Dystonia 31	619565

Associated With aopep Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR014782	Peptidase M1, membrane alanine aminopeptidase
Domain	IPR015211	Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal
Family	IPR033577	Aminopeptidase O
Homologous_superfamily	IPR016024	Armadillo-type fold
Homologous_superfamily	IPR027268	Peptidase M4/M1, CTD superfamily
Homologous_superfamily	IPR038502	Peptidase M1, LTA-4 hydrolase/aminopeptidase, C-terminal domain superfamily
Homologous_superfamily	IPR042097	Aminopeptidase N-like , N-terminal domain superfamliy

Domain Details Per Protein

Protein	Length	Aminopeptidase N-like , N-terminal domain superfamliy	Aminopeptidase O	Armadillo-type fold	Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal	Peptidase M1, LTA-4 hydrolase/aminopeptidase, C-terminal domain superfamily	Peptidase M1, membrane alanine aminopeptidase	Peptidase M4/M1, CTD superfamily
UniProtKB:B0V1A5 InterPro	787

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	aopep-206 (1) Ensembl	Ensembl	2,364 nt	Select Tool ZFIN BLAST
mRNA	zgc:162939-201 (1) Ensembl	Ensembl	2,626 nt	Select Tool
mRNA	zgc:162939-202 (1) Ensembl	Ensembl	799 nt	Select Tool
mRNA	zgc:162939-204 (1) Ensembl	Ensembl	760 nt	Select Tool
mRNA	zgc:162939-205 (1) Ensembl	Ensembl	987 nt	Select Tool
ncRNA	zgc:162939-005 (1) Ensembl	Ensembl	824 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations